Tempera paints contain organic compounds that make them safe to use, even if ingested, but this also means they eventually will spoil. To prevent spoilage, Blick recommends that you close the lid tightly after use and avoid returning unused liquid tempera to its original container after exposure to air. Always store tempera paints in their original containers, in a cool, dry place.

Dick Blick also sells Egg Tempera, an artist quality paint that resembles the original paints used in fresco and hardboard painting during the Renaissance.